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The Edge, 18 Feb 2008

Net Value, Aurigene comes to Malaysia
 
By Toh Mei Ling

Developing a new economic sector has never been an easy task seeing that there are no clear step-by-step methods that ensure the success of the endeavour. In the past, Malaysia has always looked to attracting foreign direct investment as a part of its developmental strategy. Three years after its inception, Malaysian Biotechnology Corp (BiotechCorp) has formed its first strategic alliance with Indian drug research company Aurigene Discovery Technologies Ltd. A wholly owned subsidiary of India's third largest pharmaceutical company, Dr Reddy's Laboratories, Aurigene will be setting up three functional labs here in Technology Park Malaysia. The company was recently awarded BioNexus status.

"To us, this is something that is very significant in the developmental initiatives that we are doing. India, back in 2006, recorded the second highest growth in number of patents worldwide. It is clear that India is emerging as a superpower in science and technology innovation. This is why we are collaborating with companies in India. We are also very selective — people have asked me where are the Dell equivalents in biotech and to be honest, to bring these companies in, Malaysia would have to pay through its ears. Is it really worth it?" asks Datuk Iskandar Mizal Mahmood, CEO of BiotechCorp.

He adds that BiotechCorp takes a different strategic view when looking for partners, focusing more on value creation and building of the ecosystem rather than purely job creation. Giving the example of Aurigene, Iskandar explains that the key objective is to improve drug discovery capabilities in Malaysia. Incorporated in 2002, Aurigene started as a drug discovery company that is focused on collaborations with large pharmaceutical firms. Initially, it had two facilities — Bangalore and Boston — but the latter has been shut down following the improvement of intellectual property laws in India.

"Aurigene was not set up for the purpose of cost arbitrage. Right from the beginning, we have a well- drawn-out focus whereby we are in the business of generating IP as the end product. We do very high quality work and that is why our business model is different from that of the outsourcing model. We do not need to double people in order to double revenue. We have three focus areas — oncology, metabolic disorders and inflammation. From a science focus, we do largely structure-based drug design," says C S N Murthy, Aurigene's CEO.

In the past two to three years, Aurigene has started collaborations with big pharmaceutical names like Johnson & Johnson's, Rio Science in Denmark and AmGen in the US. The company doubled its revenue in 2007, he adds, and is expected to continue its impressive growth this year. Last year alone, Aurigene filed 14 patents. Operating out of India has significantly lowered the cost of failure in R&D, while the value of the discovery remains the same: "In India, we can fail for one third or a quarter of the cost if it was done elsewhere," Murthy says.

One of the reasons why Aurigene opted to locate in Malaysia was because of the reliability of the logistics industry here, and the ease of which it could import materials. Aside from this, BiotechCorp has been encouraging interaction between the company and local universities: "We have met a few students from Universiti Malaya and with the right opportunity, we can turn these people into assets. Our operations are not very people intensive — it is about a few good people," he explains.

Although the setting up of its US$2 million (about RM6.5 million) facility is currently in its pilot phase, Murthy says Aurigene is clear on what it wants to do with the facility. Taking a careful stance, he adds that the company would like to really experience how different it is operating out of Malaysia and get familiar with the workings of the country first before really moving forward more rapidly. The plan is to start with between 15 and 20 people, but there are plans to scale up to about 50 in the next two years. The Malaysian facility will be focusing on R&D for drug metabolism and pharmacokinetics as well as cell biology.

Although BiotechCorp has equal focus on all areas of biotechnology, the healthcare spectrum seem to dominate the local scene. Of this, Iskandar says: "Of the 42 BioNexus companies, 19 are actually in the area of healthcare. The approved investments that are coming in from these companies are quite good as well and we do also have a good pipeline in terms of the companies that we are evaluating and those we are assisting to nurture in healthcare biotechnology. In India, biotechnology is a huge industry that is recording growth rates of 20% to 30% for the next five to seven years. Its healthcare biotechnology sector alone is valued at over US$2 billion."

No doubt, BiotechCorp will be hoping to see similar growth in Malaysia.
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